The use of beads with pore size > 30 nm allows the coating of the pores with a thin LbL layer. With the corresponding functions on the LbL surface, a specific affinity to materials can be attained, without large reduction of the inner surface. The coating with an LbL layer is fixed as is the hole bored by a focussed laser ray (FRAP experiment) as shown by the particles illlustrated in the figure. In cases of specific affinity of the surface, these particles are suitable as capture materials.
Functionalized Capture Beads
Left: Coating of the pores in chromaticographic particles with LbL.
Right: Confocal photograph of a particle (Ø 10 µm) and its 30 nm-sized pores coated with PAH-Cy5/PSS. The name has been written into the fixed LbL matrix using a laser (image size16 µm x 16 µm).